The optimal dosage levels of CBD are uncertain due to a lack of human studies. Chronic high doses of up to 1500 mg per day are well tolerated and produce no noticeable physiological effects. However, there is evidence to suggest that the medical benefits of CBD disappear when dosages become excessive. For inhaled medical use, most users prefer varieties with THC:CBD ratios between 2:1 and 1:2. Extremely low-THC varieties are useful for making CBD extracts and tinctures. Unlike THC, CBD does not show up positive on standard drug tests for marijuana.
Thanks so much for posting this, Dr. Fudin. As an Ehlers-Danlos patient with a keen interest in science, it frustrates me when people can’t get their facts right. If Vicodin is the same thing as heroin, then we might as well say that Maxalt (rizatriptan benzoate) is the same thing as a tricyclic antidepressant because both can contribute to serotonin syndrome. The website for the PBS documentary “The Botany of Desire” outlined the chemical differences between different kinds of opiates quite clearly; interested readers might want to check it out. (I can’t find a link, though.) I have never taken hydrocodone, but I used to use Tylenol w/ codeine in the past for acute pain. Now that I live in New York, I can’t even get a prescription for that. As a result, I’ve had to make a prescription for 20 Tylenol 3 stretch over the course of a year and a half. Some people would be gracious and say that they would never wish their pain on their worst enemy, but if my enemy worked for the FDA, I certainly would. Maybe it would provoke a change of perspective. Thank you for your advocacy.