The formation of gallstones is probably one of the major causes of blockage in the bile ducts. This also results in the formation of stones of different sizes in the gallbladder that create a blockage in the common bile duct present at the liver base. In the event the duct continues to stay blocked waste matter starts getting collected in the bloodstream as well as the system of the bile duct. You may also develop a severe infection known as ascending cholangitis, if bacteria accumulates with the blockage and retreats into the liver. If the gallstone stops between the gallbladder and the common bile duct, an infection known as cholecystitis could result.
Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are