Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are
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As a mild steroid, while most men who supplement will use it while dieting they will still need to take a fairly large amount to gain any positive effect. If you supplement with oral Primo you will need even more per week than if you choose injectable and as both are very expensive; as you can guess this cost will add up very fast. Most men who try Primobolan and who are disappointed on the basis of no results are usually found lacking simply because they didn’t take enough; for example, an average man will need approximately 500mg per week of injectable Primo to receive a benefit and he will need to do so for at least 8 weeks . Yes, you can absolutely take more and for a longer period of time but if you do be prepared to feel your wallet get a whole lot lighter.
You may have already guessed, while Primobolan can be used by men if we were to recommend it to anyone it would be the female performance enhancer first; not only because it will be tolerated so well by her but because she will not need nearly as much making it all the more affordable and feasible. Again, injectable Primo will prove to be best but to ensure safety and protection against virilization is in place most women will not want to exceed 6 weeks of use max with 4 weeks of use generally being the minimal time frame. For women who want more they can absolutely run another course but it is advised that 4 weeks of discontinued use be held to before another course begins. For the average woman most will find 100mg per week to be sufficient; you can go higher but the higher you go the greater the risk. You may need to play with the dosing a little bit but 100mg is a good place to start and 2 injections per week of 50mg each is just about perfect.